Butanedione → HCID 11171837, compound

HRID 970948Notes

Reaction equation

HRID 970948 reaction equation
[CH3:1][C:2](=O)[C:3](=O)[CH3:4].[NH2:7][CH2:8][CH2:9][NH:10][CH2:11][CH2:12][CH2:13][NH:14][CH2:15][CH2:16][NH2:17]>C(#N)C>[CH3:1][C:2]12[C:3]3([CH3:4])[N:14]([CH2:13][CH2:12][CH2:11][N:10]3[CH2:9][CH2:8][NH:7]1)[CH2:15][CH2:16][NH:17]2

Participants

4

Reactant 2

HCID 650ButanedioneHCID 78479N,N'-Bis(2-aminoethyl)-1,3-propanediamine

Product 1

HCID 11171837HCID 11171837, compound

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent2×

Procedure

A solution of 5.37 g (62.4 mmol) of butanedione in 30 ml of acetonitrile is slowly added dropwise to a solution of 10.00 g (62.4 mmol) of commercial N,N′-bis (2-aminoethyl)-1,3-propanediamine in 100 ml of acetonitrile at 0° C. The mixture is maintained at this temperature for two hours. After evaporating the solvent, compound 1 is isolated quantitatively in the form of a yellow solid and is used for the following stage without subsequent purification.

Workup

  1. temperatureThe mixture is maintained at this temperature for two hours
  2. customAfter evaporating the solvent

Sources & evidence

ORD record
ord-ac6c377db6454ea1861bdaa90d048c92
Source dataset
uspto-grants-2007_12
Patent number
US07312327B2

Reaction notes

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