HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 22860484, compound → Propanoic acid, 2-methyl-3-(methylsulfonyl)-, (S)-
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 22860484 | HCID 22860484 | — |
| Solvent | 1,4-Dioxane hydrochloride | HCID 20443148 | — |
| Product | Propanoic acid, 2-methyl-3-(methylsulfonyl)-, (S)- | HCID 15814191 | 71.9% |
Reaction Steps
To 2.68 g of 2(S)-methyl-3-(methylsulfonyl)propionic acid t-butyl ester was added 20 mL of 4N hydrochloric acid/dioxane and the mixture stirred at room temperature for 19 hours. The solvent was removed in vacuo to afford 2.18 g of crude product, which was recrystallized from ethyl acetate/hexane to yield 1.44 g of 2(S)-methyl-3-(methylsulfonyl)-propionic acid as white crystals:
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07312333B2 |
| Source dataset | uspto-grants-2007_12 |
| ORD ID | ord-aa92313f29434ad18bbe45ff69e3d80b |
| Source note | uspto-grants-2007_12 |