Ammonium formate → N-(4-tert-butylphenyl)-5,6,7,8-tetrahydro-2-(methoxymethyl)pyrido[3,4-d]pyrimidin-4-amine

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Reaction Steps

The title compound was prepared using the general procedure set forth in Example 3.A. using N-(4-tert-butylphenyl)-7-benzyl-5,6,7,8-tetrahydro-2-(methoxymethyl)pyrido[3,4-d]pyrimidin-4-amine (0.453 g, 1.09 mmol), ammonium formate (0.69 g, 10.87 mmol), palladium, 10% wt. on activated carbon (100 mg) and MeOH (15 mL). 0.334 g (94%) Of the title compound was obtained as a white foam.

Provenance & Evidence