1,4-Benzodioxan-6-ylamine → HCID 12004392, compound

HRID 971198Notes

Reaction equation

HRID 971198 reaction equation
[O:1]1[CH2:6][CH2:5][O:4][C:3]2[CH:7]=[C:8]([NH2:11])[CH:9]=[CH:10][C:2]1=2.[CH2:12]([N:19]1[CH2:28][CH2:27][C:26]2[C:25](Cl)=[N:24][CH:23]=[N:22][C:21]=2[CH2:20]1)[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1>C(#N)C>[CH2:12]([N:19]1[CH2:28][CH2:27][C:26]2[C:25]([NH:11][C:8]3[CH:9]=[CH:10][C:2]4[O:1][CH2:6][CH2:5][O:4][C:3]=4[CH:7]=3)=[N:24][CH:23]=[N:22][C:21]=2[CH2:20]1)[C:13]1[CH:14]=[CH:15][CH:16]=[CH:17][CH:18]=1

Participants

4

Reactant 2

HCID 891481,4-Benzodioxan-6-ylamineHCID 219588387-Benzyl-4-chloro-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine

Product 1

HCID 12004392HCID 12004392, compound

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Procedure

The title compound was prepared using the general procedure set forth in Example 2, above, using 2,3-dihydrobenzo[b][1,4]dioxin-6-amine (0.32 mL, 2.63 mmol) and 7-benzyl-4-chloro-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine (0.621 g, 2.39 mmol) in acetonitile (3 mL).

Sources & evidence

ORD record
ord-0eede49afc7c43b9929f65e45d155b4d
Source dataset
uspto-grants-2007_12
Patent number
US07312330B2

Reaction notes

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