Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Sodium Iodide | HCID 5238 | — |
| Reactant | 7-amino-4-methyl-2H-1,4-benzoxazine | HCID 11217429 | — |
| Reactant | 4-Chloro-7-(3-chloropyridin-2-yl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine | HCID 59021478 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | HCID 12004098 | HCID 12004098 | 16.3% |
Reaction Steps
4-Chloro-7-(3-chloropyridin-2-yl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine (112 mg, 0.36 mmol) and 3,4-dihydro-4-methyl-2H-benzo[b][1,4]oxazin-7-amine (130 mg, 0.72 mmol) were dissolved in CH3CN (3 mL), Sodium iodide (10 mg, 0.06 mmol) was added and the reaction was heated via microwave at 180° C. for 40 minutes. Solvent was removed and the residue was purified by preparative TLC to obtain the product as a beige foam (24 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07312330B2 |
|---|
| Source dataset | uspto-grants-2007_12 |
|---|
| ORD ID | ord-d352224a9a3d4dc9961758362e045cea |
|---|
| Source note | uspto-grants-2007_12 |
|---|
