HCID 59021684, compound → HCID 11626867, compound

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Reaction Steps

4-ethoxy-N-(4-methylphenyl)-N-{2-[(2E)-2-(2-nitrobenzylidene)hydrazino]-2-oxoethyl}benzenesulfonamide (99 mg, 0.2 mmol) was dissolved in methylene chloride. Palladium 5% on charcoal was added (10 mol %). The mixture was stirred under H2 at athmospheric pressure at room temperature overnight. It was filtered on Celite and solvents were evaporated. The expected product, e.g. N-{2-[(2E)-2-(2-aminobenzylidene)hydrazino]-2-oxoethyl}-4-ethoxy-N-(4-methylphenyl)benzenesulfonamide (71.2 mg, 76%), was obtained as a light yellow solid, in 90.9% purity by HPLC (MaxPlot detection between 230 and 400 nm).

Provenance & Evidence