HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Chloroaniline → N-({4-Chloro[(4-ethoxyphenyl)sulfonyl]anilino}acetyl)valine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Chloroaniline | HCID 7812 | — |
| Reactant | Methyl bromoacetate | HCID 60984 | — |
| Reactant | 4-Ethoxybenzene-1-sulfonyl chloride | HCID 3688334 | — |
| Reactant | Fmoc-N-methyl-DL-valine | HCID 5164404 | — |
| Product | N-({4-Chloro[(4-ethoxyphenyl)sulfonyl]anilino}acetyl)valine | HCID 68615009 | — |
Reaction Steps
Following the general method as outlined in Example 75, starting from N-fmoc-3-methyl-2-methylamino-butyric acid, methyl bromoacetate, 4-chloroaniline and 4-ethoxybenzenesulfonyl chloride, the title compound was obtained in >60% purity by LC/MS. (ESI+): 483.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07312358B2 |
| Source dataset | uspto-grants-2007_12 |
| ORD ID | ord-4b392c65fe234e3b9c4d25e6ee06d513 |
| Source note | uspto-grants-2007_12 |