2-Thiopheneacetic acid → HCID 21313682, compound

HRID 971381Notes

Reaction equation

HRID 971381 reaction equation
[S:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[CH2:6][C:7]([OH:9])=[O:8].[F:10][C:11]([F:22])([F:21])[C:12]1[CH:13]=[C:14]([CH:18]=[CH:19][CH:20]=1)[C:15](Cl)=[O:16]>>[F:10][C:11]([F:21])([F:22])[C:12]1[CH:13]=[C:14]([CH:18]=[CH:19][CH:20]=1)[C:15]([C:5]1[S:1][C:2]([CH2:6][C:7]([OH:9])=[O:8])=[CH:3][CH:4]=1)=[O:16]

Participants

3

Reactant 2

HCID 159702-Thiopheneacetic acidHCID 752573-(Trifluoromethyl)benzoyl chloride

Product 1

HCID 21313682HCID 21313682, compound

Procedure

Using the procedure of Example 1, 7.1 gm of thiophene-2-acetic acid and 10.40 gm of m-trifluoromethyl-benzoyl chloride were reacted to obtain 5(m-trifluoromethyl-benzoyl)-thiophene-2-acetic acid melting at 120° C.

Workup

  1. customwere reacted

Sources & evidence

ORD record
ord-3c0b781b8a06478fa71bafac545edc93
Source dataset
uspto-grants-1979_07
Patent number
US04159986

Reaction notes

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