HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → p-Trifluoromethylbenzyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 4-(Trifluoromethyl)benzenemethanol | HCID 67684 | — |
| Product | p-Trifluoromethylbenzyl chloride | HCID 123096 | — |
Reaction Steps
Thionyl chloride (15.0 g) was added to 4-(trifluoromethyl)benzenemethanol (15.0 g) over 30 min. The mixture was heated at reflux for 2 hr and then evaporated. The residue was distilled to afford the product as a colourless liquid b.p. 88°-92°/14 mm (11.0 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04160036 |
| Source dataset | uspto-grants-1979_07 |
| ORD ID | ord-d4f7dc5aee0e4cd29118328928ecf4d0 |
| Source note | uspto-grants-1979_07 |