5,6,7,8-Tetrahydroquinoline → HCID 178506835, compound

HRID 971494Notes

Reaction equation

HRID 971494 reaction equation
[CH2:1]([Li:5])[CH2:2][CH2:3][CH3:4].[N:6]1[C:15]2CCCC[C:10]=2[CH:9]=[CH:8][CH:7]=1.N1C2C(C(=S)N)CCCC=2C=CC=1>>[Li:5][CH:1]1[C:15]2[N:6]=[CH:7][CH:8]=[CH:9][C:10]=2[CH2:4][CH2:3][CH2:2]1

Participants

4

Reactant 3

HCID 663355,6,7,8-TetrahydroquinolineHCID 122782125,6,7,8-Tetrahydroquinoline-8-carbothioamideHCID 178418339Butyllithium

Product 1

HCID 178506835HCID 178506835, compound

Procedure

The title compound is prepared using n-butyl lithium (9% w/v in hexane) and 5,6,7,8-tetrahydroquinoline by the general procedure of Example 7. The product may be converted to 5,6,7,8-tetrahydroquinoline-8-thiocarboxamide by the procedures described in Example 2 above, and U.S. Ser. No. 460,265.

Sources & evidence

ORD record
ord-a1688e6531ba4b20bc9ae64b9d7b6e61
Source dataset
uspto-grants-1979_07
Patent number
US04160094

Reaction notes

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