HCID 12278209, compound → HCID 178506825, compound

Participants

Reaction Steps

By the method described in Example 7 using n-butyl lithium solution (9% w/v, 57 ml, 0.077 mol), and 2-methyl-4-phenyl-5,6,7,8-tetrahydroquinoline, the title compound is prepared and converted in situ to methyl 2-methyl-4-phenyl-5,6,7,8-tetrahydroquinoline-8-carboxylate and then to the corresponding 8-thioamide by the procedure described in U.S. Ser. No. 460,265.

Provenance & Evidence