HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Methyl-5,6,7,8-tetrahydroquinoline → HCID 178506833, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Methyl-5,6,7,8-tetrahydroquinoline | HCID 120028 | — |
| Reactant | Butyllithium | HCID 178418339 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Solvent | Hexane | HCID 8058 | — |
| Product | HCID 178506833 | HCID 178506833 | — |
Reaction Steps
A solution of n-butyl-lithium (15% w/w, 36 ml, 0.05 mole) in hexane was added portionwise to a stirred solution of 3-methyl-5,6,7,8-tetrahydroquinoline (7.3 g, 0.05 mole) in dry tetrahydrofuran (50 ml.) at 0° under nitrogen. After the addition the solution was stirred for 0.5 hour to give a dark red solution of 8-lithio-3-methyl-5,6,7,8-tetrahydroquinoline.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04160094 |
| Source dataset | uspto-grants-1979_07 |
| ORD ID | ord-1887102c2bfb4936b1d086df71816f8a |
| Source note | uspto-grants-1979_07 |