4-Chloroaniline → HCID 21313260, compound

Participants

Reaction Steps

A solution of 7.6 g (0.06 mol) p-chloroaniline and 7.0 g (0.03 mol) trichlorovinylsulfonyl chloride in 150 ml chloroform was heated under reflux for 3 hours. The reaction mixture was then cooled, washed with water, dried over magnesium sulfate and evaporated to give an oily residue. The residue was chromatographed on silica gel. N-(p-chlorophenyl)trichlorovinylsulfonamide, m.p. 73°-76° C., was eluted from the silica gel with 30% ether-70% hexane. Elemental analysis for C8H5Cl4NO2S showed: calculated, %S, 9.99, %Cl 44.2; found, %S, 10.1, %Cl 48.2.

Provenance & Evidence