Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-Propanol, 3-[[2-nitro-4-(trifluoromethyl)phenyl]amino]- → 3-{[2-Amino-4-(trifluoromethyl)phenyl]amino}-1-propanol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-Propanol, 3-[[2-nitro-4-(trifluoromethyl)phenyl]amino]- | HCID 2847509 | — |
| 반응물 | HCID 178418361 | HCID 178418361 | — |
| 촉매 | Nickel | HCID 935 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | 3-{[2-Amino-4-(trifluoromethyl)phenyl]amino}-1-propanol | HCID 20385552 | 100% |
반응 단계
A mixture of 141 parts of 3-{[2-nitro-4-(trifluoromethyl)phenyl]amino}-1-propanol and 1200 parts of methanol is hydrogenated at normal pressure and at room temperature with 15 parts of Raney-nickel catalyst. After the calculated amount of hydrogen is taken up, the catalyst is filtered off and the filtrate is evaporated. The residue is crystallized from 2,2'-oxybispropane, yielding 110 parts (100%) of 3-{[2-amino-4-(trifluoromethyl)phenyl]amino}-1-propanol.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04160836 |
| 출처 데이터셋 | uspto-grants-1979_07 |
| ORD ID | ord-8b7c6f4f67a941bc8aaf7d7840f58373 |
| 출처 메모 | uspto-grants-1979_07 |