HCID 12502754, compound → HCID 21311932, compound

HRID 971835Notes

Reaction equation

HRID 971835 reaction equation
C(C#N)(=[O:5])C(C)C.[Cl:8][CH2:9][CH2:10][CH2:11][C:12]([C:14]#[N:15])=[O:13]>>[Cl:8][CH2:9][CH2:10][CH2:11][C:12](=[O:13])[C:14]([NH2:15])=[O:5]

Participants

3

Reactant 2

HCID 12502754HCID 12502754, compoundHCID 21311945HCID 21311945, compound

Product 1

HCID 21311932HCID 21311932, compoundYield 87%

Procedure

The procedure was the same as that described in Example 1 except that instead of isobutyryl cyanide there were employed 131.5 grams (1.0 mole) of 4-chlorobutyryl cyanide. After recrystallization from water there were isolated 130 grams (87% of theory) of 5-chloro-2-oxovaleramide having a melting point of 87° C.

Workup

  1. customAfter recrystallization from water

Sources & evidence

ORD record
ord-a01727ce971e4357a525cbb91ff094ca
Source dataset
uspto-grants-1979_07
Patent number
US04161491

Reaction notes

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