Sodium Hydroxide → 3-(1-Pyrrolidinyl)-4-phenoxy-5-nitrobenzoic acid

HRID 971886Notes

Reaction equation

HRID 971886 reaction equation
C[O:2][C:3](=[O:25])[C:4]1[CH:9]=[C:8]([N+:10]([O-:12])=[O:11])[C:7]([O:13][C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)=[C:6]([N:20]2[CH2:24][CH2:23][CH2:22][CH2:21]2)[CH:5]=1.[OH-].[Na+]>>[N:20]1([C:6]2[CH:5]=[C:4]([CH:9]=[C:8]([N+:10]([O-:12])=[O:11])[C:7]=2[O:13][C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[C:3]([OH:25])=[O:2])[CH2:24][CH2:23][CH2:22][CH2:21]1

Participants

3

Reactant 2

HCID 14798Sodium HydroxideHCID 124983403-(1-Pyrrolidinyl)-4-phenoxy-5-nitrobenzoic acid methyl ester

Product 1

HCID 213121373-(1-Pyrrolidinyl)-4-phenoxy-5-nitrobenzoic acid

Procedure

50 g of 3-(1-pyrrolidinyl)-4-phenoxy-5-nitrobenzoic acid methyl ester (preparation cf Example 34, step b) are saponified under heating with dilute sodium hydroxide solution.

Sources & evidence

ORD record
ord-eedbf3024dab46d1bcc59ac2f21f913b
Source dataset
uspto-grants-1979_07
Patent number
US04161531

Reaction notes

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