Benzene → HCID 21312565, Verbindung

HRID 971921Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 971921
[CH2:1]([C:3]1([CH2:12][CH3:13])[C:8](=[O:9])[NH:7][C:6](=[O:10])[NH:5][C:4]1=[O:11])[CH3:2].Cl[CH2:15][CH2:16][CH2:17][C:18]([O:20][CH3:21])=[O:19].[C:22](=[O:25])([O-])[O-:23].[K+].[K+].[CH:28]1[CH:33]=CC=C[CH:29]=1.[CH3:34]N(C)C=O>>[CH3:21][O:20][C:18]([CH2:17][CH2:16][CH2:15][N:7]1[C:8](=[O:9])[C:3]([CH2:1][CH3:2])([CH2:12][CH3:13])[C:4](=[O:11])[N:5]([CH2:29][CH2:28][CH2:33][C:22]([O:23][CH3:34])=[O:25])[C:6]1=[O:10])=[O:19]

Komponenten

6

Edukt 5

HCID 241BenzeneHCID 2294BarbitalHCID 6228DimethylformamideHCID 11430Potassium CarbonateHCID 76612Butanoic acid, 4-chloro-, methyl ester

Produkt 1

HCID 21312565HCID 21312565, Verbindung

Versuchsvorschrift

18.4 g (0.1 mol) of 5,5-diethylbarbituric acid are reacted with 28.7 g (0.21 mol) of methyl γ-chlorobutyrate according to Example 1. 15.2 g (0.11 mol) of potassium carbonate powder are used as the acid acceptor and 100 ml of benzene and 100 ml of dimethylformamide are used as the solvent. The reaction is carried out exactly according to Example 1 and likewise worked up. In this manner, 38.3 g (99.7% of theory) of a clear, slightly discoloured viscous product are obtained.

Aufarbeitung

  1. customIn this manner, 38.3 g (99.7% of theory) of a clear, slightly discoloured viscous product are obtained

Quellen und Nachweise

ORD-Eintrag
ord-38018ddc63f14eb8b330d469b9e561c9
Quelldatensatz
uspto-grants-1979_07
Patentnummer
US04161603

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