HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(Dimethylamino)-1-octen-3-one → 3-(Dimethylamino)dec-1-YN-5-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(Dimethylamino)-1-octen-3-one | HCID 54563082 | — |
| Reactant | HCID 178464377 | HCID 178464377 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | 3-(Dimethylamino)dec-1-YN-5-one | HCID 21312635 | — |
Reaction Steps
A mixture of 1-(dimethylamino)-1-octen-3-one (4.0 g), described in Example 37, and lithiumacetylide-ethyleneamine (4.0 g) in dry dioxane (25 ml) is stirred at room temperature for 45 min. The mixture is added to ice. The mixture is extracted with ether. The extract is dried (Na2SO4) and then evaporated. The residue is distilled to afford the title compound, b.p. 80°-85° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04161608 |
| Source dataset | uspto-grants-1979_07 |
| ORD ID | ord-d33def2ec10e4f3d91063b6b9eedba80 |
| Source note | uspto-grants-1979_07 |