Chloroform → HCID 22764381, compound

Participants

Reaction Steps

2-Methyl-3-phenyl-5,6-dihydro-imidazo[2,1-b]thiazole (6.0 g., 0.027 mole) (prepared by basification of the hydrobromide salt with sodium carbonate solution and extraction into chloroform) and cetyl bromide (9.15 g., 0.03 mole) were refluxed in acetonitrile (50 ml.) for 12 hours. A crystalline solid separated on cooling which was collected and recrystallized from acetonitrile to yield 7-cetyl-2-methyl-3-phenyl--5,6-dihydro-imidazo[2,1-b]thiazolium bromide (12.2 g., 87%), m.p. 111°-113° C. (Found: C, 64.8; H, 8.6; N, 4.9. C28H45N2SBr requires C, 64.5; H, 8.6; N, 5.4%).

Provenance & Evidence