HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetyl chloride → 7-Acetyl-6-ethyl-1,1,4,4-tetramethyltetralin
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetyl chloride | HCID 6367 | — |
| Reactant | Naphthalene, 6-ethyl-1,2,3,4-tetrahydro-1,1,4,4-tetramethyl- | HCID 6663 | — |
| Reactant | 2,2,4-Trimethylpentane | HCID 10907 | — |
| Reactant | Aluminum(III) Chloride | HCID 6451240 | — |
| Product | Naphthalene, 6-ethyl-1,2,3,4-tetrahydro-1,1,4,4-tetramethyl- | HCID 6663 | — |
| Product | 7-Acetyl-6-ethyl-1,1,4,4-tetramethyltetralin | HCID 6930 | 89% |
Reaction Steps
A solution of 1,1,4,4-tetramethyl-6-ethyl-1,2,3,4-tetrahydronaphthalene (528 grams) and acetyl chloride (234 grams) is added over a 31/2 hour period at 70° C. to a well stirred slurry of aluminum chloride (534 grams), 1,1,4,4-tetramethyl-6-ethyl-1,2,3,4-tetrahydronaphthalene (1200 grams) and isooctane (432 grams). The reaction is worked up as in Example I to afford 689 grams of 1,1,4,4-tetramethyl-6-ethyl-7-acetyl-1,2,3,4-tetrahydronaphthalene (89% based on consumed 1,1,4,4-tetramethyl-6-ethyl-1,2,3,4-tetrahydronaphthalene) and 1106 grams of recovered 1,1,4,4-tetramethyl-6-ethyl-1,2,3,4-tetrahydronaphthalene.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04162256 |
| Source dataset | uspto-grants-1979_07 |
| ORD ID | ord-6c4d0721c4bf4038980ed0710cf35b69 |
| Source note | uspto-grants-1979_07 |