反应详情

To 50 ml of a 28% aqueous ethanol solution was added 2.6 g (0.0084 mole) of 1,4-bis-(3-acetamidophenyl)-buta-1-ene-3-yne and the mixture was refluxed for 1 hour. After cooling to room temperature, the reaction mixture was poured into 300 ml of distilled water and extracted with three 100 ml portions of methylene chloride. Removal of the methylene chloride under reduced pressure provided a light yellow material. Recrystallization of the material from a one-to-one mixture of benzene/hexane gave 1 g (50% yield) of product (m.p. 105°-106° C.).

1. temperaturethe mixture was refluxed for 1 hour
2. extractionextracted with three 100 ml portions of methylene chloride
3. customRemoval of the methylene chloride under reduced pressure
4. customprovided a light yellow material
5. customRecrystallization of the material
6. additionfrom a one-to-one mixture of benzene/hexane