Maleic Anhydride → HCID 70603840, compound

HRID 971997Notes

Reaction equation

HRID 971997 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([NH:12][NH2:13])[CH:5]=[CH:6][C:7]=1[C:8]([F:11])([F:10])[F:9].[C:14]1(=[O:20])[O:19][C:17](=[O:18])[CH:16]=[CH:15]1>C1(C)C=CC=CC=1>[Cl:1][C:2]1[CH:3]=[C:4]([N:12]([C:14](=[O:20])/[CH:15]=[CH:16]\[C:17]([OH:19])=[O:18])[NH2:13])[CH:5]=[CH:6][C:7]=1[C:8]([F:11])([F:10])[F:9]

Participants

4

Reactant 2

HCID 7923Maleic AnhydrideHCID 21311702HCID 21311702, compound

Product 1

HCID 70603840HCID 70603840, compoundYield 65%

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Conditions

Temperature
50 °C

Procedure

10.5 g (0.05 mol) of 3-chloro-4-trifluoromethylphenylhydrazine were dissolved in 50 ml of toluene. 4.9 g of maleic anhydride (0.05 mol) in the solid form were introduced into this solution at room temperature. This caused the temperature to rise by a few degrees, while the reaction product precipitated in the crystalline form. The mixture was then heated to about 50° C. for some time, after which it was allowed to cool and the product was filtered off. 10 g (65% of theory) of maleic acid mono-(3-chloro-4-trifluoromethyl-phenyl)-hydrazide of melting point 180°-182° C. were obtained.

Workup

  1. customprecipitated in the crystalline form
  2. temperatureto cool
  3. filtrationthe product was filtered off

Sources & evidence

ORD record
ord-2f384044f9d8413c9021e233af9eb0bc
Source dataset
uspto-grants-1979_07
Patent number
US04162329

Reaction notes

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