HRID972016

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID14797

Potassium hydroxide

HKO

HCID75987

Bis[(oxiran-2-yl)methyl] hexanedioate

C12H18O6

HCID20481853

7,7,8,9,9-Pentamethyl-1,3,8-triazaspiro[4.5]decane-2,4-dione

C12H21N3O2

PRODUCTS

生成物

结构：CN1C(C)(C)CC2(CC1(C)C)NC(=O)N(CC(O)COC(=O)CCCCC(=O)OCC(O)CN1C(=O)NC3(CC(C)(C)N(C)C(C)(C)C3)C1=O)C2=O

HCID70611364

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID6386

tert-Butyl alcohol

C4H10O

PROCEDURE

实验过程

9.6 g of 7,7,8,9,9-pentamethyl-1,3,8-triazaspiro[4.5]decane-2,4-dione, 5.2 g of bis(2,3-epoxypropyl)adipate and 0.1 g of potassium hydroxide were reacted in 80 ml of t-butanol, following substantially the same procedure as in Example 1. The desired Compound No. 126 was obtained in the form of white crystals, melting at 180°-184° C.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-39c8ba6acc32444ebf47031239ee993d
来源数据集: uspto-grants-1979_07
DOI: 10.6084/m9.figshare.5104873.v1
专利: US04162246
来源说明: uspto-grants-1979_07

反应 SMILES

[CH3:1][C:2]1([CH3:17])[N:13]([CH3:14])[C:12]([CH3:16])([CH3:15])[CH2:11][C:4]2([NH:8][C:7](=[O:9])[NH:6][C:5]2=[O:10])[CH2:3]1.[O:18]1[CH2:35][CH:19]1[CH2:20][O:21][C:22](=[O:34])[CH2:23][CH2:24][CH2:25][CH2:26][C:27]([O:29][CH2:30][CH:31]1[O:33][CH2:32]1)=[O:28].[OH-:36].[K+]>C(O)(C)(C)C>[OH:18][CH:19]([CH2:35][N:6]1[C:5](=[O:36])[C:4]2([CH2:3][C:2]([CH3:1])([CH3:17])[N:13]([CH3:14])[C:12]([CH3:16])([CH3:15])[CH2:11]2)[NH:8][C:7]1=[O:9])[CH2:20][O:21][C:22](=[O:34])[CH2:23][CH2:24][CH2:25][CH2:26][C:27]([O:29][CH2:30][CH:31]([OH:33])[CH2:32][N:6]1[C:5](=[O:10])[C:4]2([CH2:3][C:2]([CH3:17])([CH3:1])[N:13]([CH3:14])[C:12]([CH3:16])([CH3:15])[CH2:11]2)[NH:8][C:7]1=[O:9])=[O:28]