Potassium Hydroxide → Bis[2-hydroxy-3-(7,7,8,9,9-pentamethyl-2,4-dioxo-1,3,8-triazaspiro[4.5]dec-3-yl)propyl]adipate

HRID 972016Notes

Reaction equation

HRID 972016 reaction equation
[CH3:1][C:2]1([CH3:17])[N:13]([CH3:14])[C:12]([CH3:16])([CH3:15])[CH2:11][C:4]2([NH:8][C:7](=[O:9])[NH:6][C:5]2=[O:10])[CH2:3]1.[O:18]1[CH2:35][CH:19]1[CH2:20][O:21][C:22](=[O:34])[CH2:23][CH2:24][CH2:25][CH2:26][C:27]([O:29][CH2:30][CH:31]1[O:33][CH2:32]1)=[O:28].[OH-:36].[K+]>C(O)(C)(C)C>[OH:18][CH:19]([CH2:35][N:6]1[C:5](=[O:36])[C:4]2([CH2:3][C:2]([CH3:1])([CH3:17])[N:13]([CH3:14])[C:12]([CH3:16])([CH3:15])[CH2:11]2)[NH:8][C:7]1=[O:9])[CH2:20][O:21][C:22](=[O:34])[CH2:23][CH2:24][CH2:25][CH2:26][C:27]([O:29][CH2:30][CH:31]([OH:33])[CH2:32][N:6]1[C:5](=[O:10])[C:4]2([CH2:3][C:2]([CH3:17])([CH3:1])[N:13]([CH3:14])[C:12]([CH3:16])([CH3:15])[CH2:11]2)[NH:8][C:7]1=[O:9])=[O:28]

Participants

5

Reactant 3

HCID 14797Potassium HydroxideHCID 759871,6-Bis(2-oxiranylmethyl) hexanedioateHCID 204818537,7,8,9,9-Pentamethyl-1,3,8-triazaspiro[4.5]decane-2,4-dione

Product 1

HCID 70611364Bis[2-hydroxy-3-(7,7,8,9,9-pentamethyl-2,4-dioxo-1,3,8-triazaspiro[4.5]dec-3-yl)propyl]adipate

Reagents, catalysts & solvents 1

HCID 6386tert-ButanolSolvent

Procedure

9.6 g of 7,7,8,9,9-pentamethyl-1,3,8-triazaspiro[4.5]decane-2,4-dione, 5.2 g of bis(2,3-epoxypropyl)adipate and 0.1 g of potassium hydroxide were reacted in 80 ml of t-butanol, following substantially the same procedure as in Example 1. The desired Compound No. 126 was obtained in the form of white crystals, melting at 180°-184° C.

Sources & evidence

ORD record
ord-39c8ba6acc32444ebf47031239ee993d
Source dataset
uspto-grants-1979_07
Patent number
US04162246

Reaction notes

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