HRID972018

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID14797

Potassium hydroxide

HKO

HCID21660

Bis(2,3-epoxypropyl) cyclohexane-1,2-dicarboxylate

C14H20O6

HCID20481853

7,7,8,9,9-Pentamethyl-1,3,8-triazaspiro[4.5]decane-2,4-dione

C12H21N3O2

PRODUCTS

生成物

结构：CN1C(C)(C)CC2(CC1(C)C)NC(=O)N(CC(O)COC(=O)C1CCCCC1C(=O)OCC(O)CN1C(=O)NC3(CC(C)(C)N(C)C(C)(C)C3)C1=O)C2=O

HCID86736590

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID887

Methanol

CH4O

PROCEDURE

实验过程

27.0 g of 7,7,8,9,9-pentamethyl-1,3,8-triazaspiro[4.5]decane-2,4-dione, 14.0 g of bis(2,3-epoxypropyl)1,2-cyclohexanedicarboxylate and 0.2 g of potassium hydroxide were reacted in 300 ml of methanol, following substantially the same procedure as in Example 1. The desired Compound No. 147 was obtained in the form of white crystals melting at 119°-122° C.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-a6ab9d8bdb6040da8edf848555b2864a
来源数据集: uspto-grants-1979_07
DOI: 10.6084/m9.figshare.5104873.v1
专利: US04162246
来源说明: uspto-grants-1979_07

反应 SMILES

[CH3:1][C:2]1([CH3:17])[N:13]([CH3:14])[C:12]([CH3:16])([CH3:15])[CH2:11][C:4]2([NH:8][C:7](=[O:9])[NH:6][C:5]2=[O:10])[CH2:3]1.[O:18]1[CH2:37][CH:19]1[CH2:20][O:21][C:22]([CH:24]1[CH2:29][CH2:28][CH2:27][CH2:26][CH:25]1[C:30]([O:32][CH2:33][CH:34]1[O:36][CH2:35]1)=[O:31])=[O:23].[OH-:38].[K+]>CO>[OH:18][CH:19]([CH2:37][N:6]1[C:5](=[O:38])[C:4]2([CH2:3][C:2]([CH3:1])([CH3:17])[N:13]([CH3:14])[C:12]([CH3:16])([CH3:15])[CH2:11]2)[NH:8][C:7]1=[O:9])[CH2:20][O:21][C:22]([CH:24]1[CH2:29][CH2:28][CH2:27][CH2:26][CH:25]1[C:30]([O:32][CH2:33][CH:34]([OH:36])[CH2:35][N:6]1[C:5](=[O:10])[C:4]2([CH2:3][C:2]([CH3:17])([CH3:1])[N:13]([CH3:14])[C:12]([CH3:16])([CH3:15])[CH2:11]2)[NH:8][C:7]1=[O:9])=[O:31])=[O:23]