Potassium Hydroxide → Nonaethylene glycol bis[2-hydroxy-3-(7,7,8,9,9-pentamethyl-2,4-dioxo-1,3,8-triazaspiro[4.5]dec-3-yl)propyl]ether

Participants

Reaction Steps

5.8 g of 7,7,8,9,9-pentamethyl-1,3,8-triazaspiro[4.5]decane-2,4-dione, 5.3 g of nonaethylene glycol bis(2,3-epoxypropyl)ether and 0.1 g of potassium hydroxide were reacted in 100 ml of methanol, following substantially the same procedure as in Example 1. The desired Compound No. 169 was obtained in the form of a colourless, viscous liquid, having an Rf value of 0.38 on thin-layer chromatography on silica gel using a 2:1:0.03 by volume mixture of ethyl acetate, methanol and triethylamine as developing solvent.

Provenance & Evidence