反应详情

A mixture of 7.7 g of 7,7,9,9-tetramethyl-1,3,8-triazaspiro[4.5]decane-2,4-dione, 2.5 g of ethylene glycol bis(2,3-epoxypropyl)ether and 0.1 g of potassium hydroxide in 80 ml of methanol was refluxed for 11 hours. Insoluble materials were then filtered off and the filtrate was washed with hot methanol. The solution was dried and then the solvent evaporated off. The residue was recrystallised from N,N-dimethylformamide, giving the desired compound in the form of white crystals, melting at 262°-264° C.

1. temperaturewas refluxed for 11 hours
2. filtrationInsoluble materials were then filtered off
3. washthe filtrate was washed with hot methanol
4. customThe solution was dried
5. customthe solvent evaporated off
6. customThe residue was recrystallised from N,N-dimethylformamide