Methyl iodide → HCID 15850213, compound

HRID 972034Notes

Reaction equation

HRID 972034 reaction equation
[CH3:1][N:2]1[C:6]([C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=2)=[CH:5][C:4]([C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)=[N:3]1.[CH3:19][I:20]>C1C=CC=CC=1>[I-:20].[CH3:1][N+:2]1[N:3]([CH3:19])[C:4]([C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)=[CH:5][C:6]=1[C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1

Participants

4

Reactant 2

HCID 6328Methyl iodideHCID 1405171-Methyl-3,5-diphenylpyrazole

Product 1

HCID 15850213HCID 15850213, compoundYield 15%

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent

Procedure

5.0 Grams of 1-methyl-3,5-diphenylpyrazole is dissolved in 30 ml. of dry benzene with heating and constant stirring. 30.4 Grams of methyl iodide is added to the mixture, and the mixture heated to reflux. After refluxing for 12 hours, the mixture is cooled and filtered. The filtrate is again refluxed and as product forms, it is separated from the mixture by filtration. The total amount of solid recovered is 1.21 grams, 15% yield, having a melting point of 167° C. to 169° C.

Workup

  1. temperaturethe mixture heated to reflux
  2. temperatureAfter refluxing for 12 hours
  3. temperaturethe mixture is cooled
  4. filtrationfiltered
  5. temperatureThe filtrate is again refluxed and as product forms, it
  6. customis separated from the mixture by filtration
  7. customThe total amount of solid recovered

Sources & evidence

ORD record
ord-7ca3cb9da6d44e049d2144fe2fc20443
Source dataset
uspto-grants-1979_07
Patent number
US04162913

Reaction notes

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