HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → HCID 20559517, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | N-Methylaniline | HCID 7515 | — |
| Reactant | 2-(3-Chloropropyl)-2-methyl-1,3-dioxolane | HCID 80079 | — |
| Reactant | Sodium Bicarbonate | HCID 516892 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | HCID 20559517 | HCID 20559517 | — |
Reaction Steps
To 49.4 g (0.30 mol) 5-chloro-2-pentanone ethylene ketal and 64.2 g (0.60 mol) N-methylaniline in 100 ml toluene, add 27.7 g (0.33 mol) NaHCO3 and 2.0 g KI. Reflux with a water separator overnight. Allow to cool, filter, and concentrate. Distill at 50°/0.1 mm to remove N-methylaniline. Stir the residual liquid with 175 ml 1.0 N HCl for 2 hrs. Neutralize with NaHCO3 and extract with ether. Dry, concentrate, and distill to collect a fraction of b.p. 103°-110° /0.1 mm.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04163053 |
| Source dataset | uspto-grants-1979_07 |
| ORD ID | ord-dd25a3e2508944d8a12f36f1a9a85fc2 |
| Source note | uspto-grants-1979_07 |