HuagongsheHuagongshe Chemistry Print Report · For research reference only
Butylamine → N-Butyl-3-methyl-1,2,4-oxadiazol-5-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Butylamine | HCID 8007 | — |
| Reactant | 3-Methyl-5-(trichloromethyl)-1,2,4-oxadiazole | HCID 70953 | — |
| Product | N-Butyl-3-methyl-1,2,4-oxadiazol-5-amine | HCID 20393636 | — |
Reaction Steps
3-Methyl-5-trichloromethyl-1,2,4-oxadiazole (43 g, 0.21 mole) was added to n-butylamine (46.75 g, 0.63 mole) and stirred at room temperature overnight. Excess amine was removed under vacuum and the residue distilled (oil bath 110° C./0.5 mm Hg). Recrystallisation fromm petroleum ether 60°-80° C. gave the title compound as white plates 26 g, m.p. 62°-65° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04163048 |
| Source dataset | uspto-grants-1979_07 |
| ORD ID | ord-1f11e51b8ea349ccade8b35962502bb4 |
| Source note | uspto-grants-1979_07 |