4-Toluenesulfonyl chloride → HCID 21406337, compound

Participants

Reaction Steps

A mixture of 10 g. of 6-(3,5-dichloro-4-hydroxyphenyl)-4,5-dihydro-3(2H)pyridazinone, 7.6 g. of p-toluenesulfonic chloride, 4 g. of triethylamine and 50 ml. of dimethylformamide was stirred at 50° C. for 8 hours. Then, the reaction mixture was treated in the same manner as in Example 11 and recrystallized from dioxane-petroleum ether to give 3.8 g. of the desired product as prisms of m.p. 208° - 209° C.

Provenance & Evidence