Thionyl Chloride → Methyl 7-phthalimido-3-methylenecepham-4-carboxylate 1-oxide

Participants

Reaction Steps

The same procedure was followed as described in Example 1 (L) above except 0.20 g. of methyl 3-methyl-2-(2-sulfino-4-oxo-3-phthalimido-1-azetidinyl)-3-butenoate was employed as the starting material instead of the corresponding sulfinyl chloride. An nmr spectrum of the product showed the title compound to be the major constituent.

Provenance & Evidence