反应详情

2.1g. of α-methylfluorene-2-acetonitrile is refluxed in 60% aqueous ethanol (50ml.) containing potassium hydroxide (5g.) until the evolution of ammonia ceases. The ethanol is evaporated and the aqueous solution acidified to pH 2.0 with HCl and extracted with ether. The ether extracts are washed with water, dried (MgSO4) and evaporated to give the title compound.

1. customThe ethanol is evaporated
2. extractionextracted with ether
3. washThe ether extracts are washed with water
4. dry with materialdried (MgSO4)
5. customevaporated