HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzoyl chloride → N-(4-nitrostyrylsulfonyl)benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzoyl chloride | HCID 7412 | — |
| Reactant | Phosphorus oxychloride | HCID 24813 | — |
| Reactant | 2-(4-Nitrophenyl)ethene-1-sulfonamide | HCID 53633180 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | N-(4-nitrostyrylsulfonyl)benzamide | HCID 54406439 | 76% |
Reaction Steps
A mixture of 4-nitrostyrylsulfonamide (18.2 g., 0.08 mole), benzoyl chloride (12.6 g., 0.09 mole) and phosphorus oxychloride (13.8 g., 0.09 mole) is heated at steam bath temperature for 105 hr. The reaction mixture diluted with 20 ml. of ethyl acetate, cooled and filtered affords 19.0 g. (76% yield) of N-(4-nitrostyrylsulfonyl)benzamide, m.p. 192°-195° C., from ethyl acetate-hexane.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04052455 |
| Source dataset | uspto-grants-1977_10 |
| ORD ID | ord-31e1cb9f2454463bb4c05d683ba4c096 |
| Source note | uspto-grants-1977_10 |