Iodobenzene → 5-Ethyl-1-phenyl-1H-pyridin-2-one

HRID 972311Notes

Reaction equation

HRID 972311 reaction equation
I[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH2:8]([C:10]1[CH:11]=[CH:12][C:13](=[O:16])[NH:14][CH:15]=1)[CH3:9]>>[CH2:8]([C:10]1[CH:11]=[CH:12][C:13](=[O:16])[N:14]([C:2]2[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=2)[CH:15]=1)[CH3:9]

Participants

3

Reactant 2

HCID 11575IodobenzeneHCID 193658715-Ethyl-2-pyridinol

Product 1

HCID 101303775-Ethyl-1-phenyl-1H-pyridin-2-oneYield 84%

Procedure

Iodobenzene when caused to react with 5-ethyl-2-(1H)-pyridone following the general procedure outlined in Example 1, an 84% yield of 5-ethyl-1-phenyl-2-(1H)-pyridone is obtained.

Sources & evidence

ORD record
ord-f4c2768575554b058be52c7be33ecc47
Source dataset
uspto-grants-1977_10
Patent number
US04052509

Reaction notes

Loading…