Iodobenzene → 5-Methyl-1,3-diphenyl-2(1H)-pyridinone

HRID 972313Notes

Reaction equation

HRID 972313 reaction equation
[CH3:1][C:2]1[CH:3]=[C:4]([C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)[C:5](=[O:8])[NH:6][CH:7]=1.I[C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1>>[C:16]1([N:6]2[CH:7]=[C:2]([CH3:1])[CH:3]=[C:4]([C:9]3[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=3)[C:5]2=[O:8])[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1

Participants

3

Reactant 2

HCID 11575IodobenzeneHCID 214067055-Methyl-3-phenyl-2(1H)-pyridinone

Product 1

HCID 98600095-Methyl-1,3-diphenyl-2(1H)-pyridinoneYield 77%

Procedure

5-Methyl-3-phenyl-2-(1H)-pyridone (B. E. Witzel, et al. Brit. Pat. 1,238,959) is reacted with iodobenzene as in Example 1 to give 1,3-Diphenyl-5-methyl-2-(1H)-pyridone in 77% yield.

Sources & evidence

ORD record
ord-27ab782b4aff451bad8a3877fcc41ec3
Source dataset
uspto-grants-1977_10
Patent number
US04052509

Reaction notes

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