HuagongsheHuagongshe Chemistry Print Report · For research reference only
Chloroacetic Acid → HCID 21403818, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Chloroacetic Acid | HCID 300 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | HCID 178527838 | HCID 178527838 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 21403818 | HCID 21403818 | 67% |
Reaction Steps
A mixture of 3-(p-chlorophenyl)-5-mercapto-1,2,4-oxadiazole (106 parts), chloroacetic acid (48 parts), potassium carbonate (75 parts) and water (100 parts) was heated at reflux for one hour. The solution was filtered hot, cooled, acidified and the solid separated to give [3-(p-chlorophenyl)-1,2,4-oxadiazol-5-ylthio]acetic acid (91 parts, 67% yield), melting point 112°-114° C. (as monohydrate).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | USRE029439 |
| Source dataset | uspto-grants-1977_10 |
| ORD ID | ord-6d6fcfb8e6a34a44a7a5b5dec4d73e6d |
| Source note | uspto-grants-1977_10 |