HuagongsheHuagongshe Chemistry Print Report · For research reference only
Chloroacetic Acid → Acetic acid, (3-phenyl-1,2,4-thiadiazol-5-yl)thio-
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Chloroacetic Acid | HCID 300 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | HCID 178527832 | HCID 178527832 | — |
| Solvent | Water | HCID 962 | — |
| Product | Acetic acid, (3-phenyl-1,2,4-thiadiazol-5-yl)thio- | HCID 36296 | 51% |
Reaction Steps
A mixture of 5-mercapto-3-phenyl-1,2,4-thiadiazole (76 parts), potassium carbonate (58 parts), chloroacetic acid (38 parts) and water (100 parts) was heated at reflux for 1 hour. The solution was filtered hot, cooled, acidified, and the solid separated to give (3-phenyl-1,2,4-thiadiazol-5-ylthio)acetic acid (50 parts, 51% yield), melting point 97° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | USRE029439 |
| Source dataset | uspto-grants-1977_10 |
| ORD ID | ord-0da77c8417494c6093a223f689123dc8 |
| Source note | uspto-grants-1977_10 |