HRID972439

反应详情

EQUATION

反应方程式

REACTANTS

反应物

反应SMILES：CCCCCCCCCCCCCCCCS(=O)(=O)Nc1cccc2ccc(O)c(N)c12

HCID54275719

未命名化合物

反应SMILES：COc1ccccc1N=Nc1ccc2c(S(=O)(=O)Cl)ccc(NC(C)=O)c2c1O

HCID135755448

未命名化合物

PRODUCTS

产物

反应SMILES：CCCCCCCCCCCCCCCCS(=O)(=O)Nc1cccc2ccc(O)c(NS(=O)(=O)c3ccc(NC(C)=O)c4c(O)c(N=Nc5ccccc5OC)ccc34)c12

HCID136409739

未命名化合物

收率 54.9%

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID1049

Pyridine

C5H5N

PROCEDURE

实验过程

To a solution of 0.85 g (0.0018 mole) crude 1-amino-8-hexadecanesulfonamido-2-naphthol in 16 ml pyridine at 0° C was added 0.81 g (0.0018 mole) 4-acetamido-5-hydroxy-6-(o-methoxyphenylazo)naphthalene-1-sulfonyl chloride. The mixture was stirred overnight at room temperature, then poured in ice water containing 18 ml concentrated hydrochloric acid. The product was dried and triturated first with hot 1:1 dioxaneisopropyl alcohol and then with hot methanol to give 0.85 g of product, m.p. 177°-180° C.

WORKUP

后处理

customThe product was dried
customtriturated first with hot 1:1 dioxaneisopropyl alcohol

来源与证据

来源类型: Open Reaction Database
ORD记录: ord-50fc1be47a2c4a63b716e83206c2b748
来源数据集: uspto-grants-1977_10
DOI: 10.6084/m9.figshare.5104873.v1
专利号: US04053312
来源说明: uspto-grants-1977_10

反应SMILES

[NH2:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][C:10]=2[NH:12][S:13]([CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH3:31])(=[O:15])=[O:14])[CH:5]=[CH:4][C:3]=1[OH:32].[C:33]([NH:36][C:37]1[C:46]2[C:41](=[CH:42][CH:43]=[C:44]([N:48]=[N:49][C:50]3[CH:55]=[CH:54][CH:53]=[CH:52][C:51]=3[O:56][CH3:57])[C:45]=2[OH:47])[C:40]([S:58](Cl)(=[O:60])=[O:59])=[CH:39][CH:38]=1)(=[O:35])[CH3:34]>N1C=CC=CC=1>[C:33]([NH:36][C:37]1[C:46]2[C:41](=[CH:42][CH:43]=[C:44]([N:48]=[N:49][C:50]3[CH:55]=[CH:54][CH:53]=[CH:52][C:51]=3[O:56][CH3:57])[C:45]=2[OH:47])[C:40]([S:58]([NH:1][C:2]2[C:11]3[C:6](=[CH:7][CH:8]=[CH:9][C:10]=3[NH:12][S:13]([CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH3:31])(=[O:15])=[O:14])[CH:5]=[CH:4][C:3]=2[OH:32])(=[O:59])=[O:60])=[CH:39][CH:38]=1)(=[O:35])[CH3:34]