HCID 70588624, compound → HCID 131710932, compound

HRID 972480Notes

Reaction equation

HRID 972480 reaction equation
[OH:1][C@@H:2]1[C:20](=[O:21])[N:4]2[C:5]([C:17]([OH:19])=[O:18])=[C:6]([CH2:9][S:10][C:11]3[S:12][C:13]([CH3:16])=[N:14][N:15]=3)[CH2:7][S:8][C@H:3]12.[F:22][C:23]([CH2:26][C:27](O)=[S:28])([F:25])[F:24]>>[F:22][C:23]([CH2:26][C:27]([O:1][C@@H:2]1[C:20](=[O:21])[N:4]2[C:5]([C:17]([OH:19])=[O:18])=[C:6]([CH2:9][S:10][C:11]3[S:12][C:13]([CH3:16])=[N:14][N:15]=3)[CH2:7][S:8][C@H:3]12)=[S:28])([F:25])[F:24]

Participants

3

Reactant 2

HCID 70588624HCID 70588624, compoundHCID 178526197HCID 178526197, compound

Product 1

HCID 131710932HCID 131710932, compound

Procedure

Reaction of 7β-hydroxy-3-(5-methyl-1,3,4-thiadiazol-2-ylthiomethyl)-3-cephem-4-carboxylic acid and trifluoromethylthioacetic acid according to the procedure of Preparation 3 gives the title compound.

Workup

  1. customto the procedure of Preparation 3

Sources & evidence

ORD record
ord-2934764d5d824c688fdbdfc012412961
Source dataset
uspto-grants-1977_10
Patent number
US04053468

Reaction notes

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