Potassium 2-ethylhexanoate → HCID 131710494, compound

Participants

Reaction Steps

To a solution of 3-methoxyiminomethyl-7β-(2-thienylacetamido)-3-cephem-4-carboxylic acid (10.1 g) in ethyl acetate (50 ml) is added a solution of potassium 2-ethylhexanoate (4.5 g) in propanol (8.9 ml), and the mixture is kept in a refrigerator for 15 hours. The crystals formed are collected by filtration, washed with ethyl acetate, and recrystallized from a mixture of methanol and ether to give potassium 3-methoxyiminomethyl-7β-(2-thienylacetamido)-3-cephem-4-carboxylate monohydrate (10.5 g). m.p. 206°-209° C. Yield: 91%.

Provenance & Evidence