Sodium Hydroxide → HCID 131710933, compound

HRID 972490Notes

Reaction equation

HRID 972490 reaction equation
[CH3:1][O:2][N:3]=[CH:4][C:5]1[CH2:6][S:7][C@@H:8]2[C@H:15]([NH:16][C:17](=[O:24])[CH2:18][C:19]3[S:20][CH:21]=[CH:22][CH:23]=3)[C:14](=[O:25])[N:9]2[C:10]=1[C:11]([OH:13])=[O:12].[OH-].[Na+:27]>O>[CH3:1][O:2][N:3]=[CH:4][C:5]1[CH2:6][S:7][C@@H:8]2[C@H:15]([NH:16][C:17](=[O:24])[CH2:18][C:19]3[S:20][CH:21]=[CH:22][CH:23]=3)[C:14](=[O:25])[N:9]2[C:10]=1[C:11]([O-:13])=[O:12].[Na+:27]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 131710493HCID 131710493, compound

Product 1

HCID 131710933HCID 131710933, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

A solution of 3-methoxyiminomethyl-7β-(2-thienylacetamido)-3-cephem-4-carboxylic acid (1 g) in water (100 ml) is neutralized with aqueous 2N-sodium hydroxide to pH 6.5. The solution is lyophylized to give a solid mass of sodium 3-methoxyiminomethyl-7β-(2-thienylacetamido)-3-cephem-4-carboxylate (1.1 g) which is readily soluble in water.

Sources & evidence

ORD record
ord-960efc2bfd574216a0527846c8b5b821
Source dataset
uspto-grants-1977_10
Patent number
US04053469

Reaction notes

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