(2-Isothiocyanatoethyl)dimethylamine → N-(2-Dimethylaminoethyl)-N'-[2-(2-pyrazinylmethylamino)ethyl]thiourea

HRID 972599Notes

Reaction equation

HRID 972599 reaction equation
[N:1]1[CH:6]=[CH:5][N:4]=[CH:3][C:2]=1[CH2:7][NH:8][CH2:9][CH2:10][NH2:11].[CH3:12][N:13]([CH3:19])[CH2:14][CH2:15][N:16]=[C:17]=[S:18]>>[CH3:12][N:13]([CH3:19])[CH2:14][CH2:15][NH:16][C:17]([NH:11][CH2:10][CH2:9][NH:8][CH2:7][C:2]1[CH:3]=[N:4][CH:5]=[CH:6][N:1]=1)=[S:18]

Participants

3

Reactant 2

HCID 3853726(2-Isothiocyanatoethyl)dimethylamineHCID 13910894N-(pyrazinylmethyl)ethylenediamine

Product 1

HCID 20557935N-(2-Dimethylaminoethyl)-N'-[2-(2-pyrazinylmethylamino)ethyl]thiourea

Procedure

By the procedure of Example 40(a), treating N-(2-pyrazinylmethyl)ethylenediamine with 2-dimethylaminoethyl isothiocyanate gives the title compound.

Sources & evidence

ORD record
ord-e052129821f94b94aacf5e7ea38f07e4
Source dataset
uspto-grants-1977_10
Patent number
US04053473

Reaction notes

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