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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 972611Generated: October 31, 2026

Benzoyl isothiocyanate → N-benzoyl-N'-[2-(3-isothiazolylmethylthio)ethyl]thiourea

https://huagongshe.com/reaction/972611

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzoyl isothiocyanateHCID 68284—
Reactant2-{[(1,2-Thiazol-3-yl)methyl]sulfanyl}ethan-1-amineHCID 12951537—
ProductN-benzoyl-N'-[2-(3-isothiazolylmethylthio)ethyl]thioureaHCID 20557677—

Reaction Steps

By the procedure of Example 18, 3-[(2-aminoethyl)thiomethyl]isothiazole is reacted with benzoyl isothiocyanate to give N-benzoyl-N'-[2-(3-isothiazolylmethylthio)ethyl]thiourea. Removing the benzoyl group by the procedure of Example 18 gives N-[2-(3-isothiazolylmethylthio)ethyl)thiourea.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04053473
Source datasetuspto-grants-1977_10
ORD IDord-12a294c6a145482caf6e00b8fe2ae622
Source noteuspto-grants-1977_10