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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 972616Generated: October 30, 2026

Benzoyl isothiocyanate → N-benzoyl-N'-[2-((4-methyl-5-oxazolyl)methylthio)ethyl]thiourea

https://huagongshe.com/reaction/972616

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzoyl isothiocyanateHCID 68284—
Reactant4-Methyl-5-[(2-aminoethyl)thiomethyl]oxazoleHCID 12543863—
ProductN-benzoyl-N'-[2-((4-methyl-5-oxazolyl)methylthio)ethyl]thioureaHCID 20557859—

Reaction Steps

5-[(2-Aminoethyl)thiomethyl]-4-methyloxazole is reacted with benzoyl isothiocyanate by the procedure of Example 18 to give N-benzoyl-N'-[2-((4-methyl-5-oxazolyl) methylthio)ethyl]thiourea. Removing the benzoyl group by the procedure of Example 18 gives N-[2-((4-methyl-5- oxazolyl)methylthio)ethyl]thiourea.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04053473
Source datasetuspto-grants-1977_10
ORD IDord-816f27292a04449e8ad2e3e2c6d36525
Source noteuspto-grants-1977_10