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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 972629Generated: October 30, 2026

(2-Isothiocyanatoethyl)dimethylamine → N-(2-Dimethylaminoethyl)-N'-[2-(2-(4-methyl-5-oxazolyl)ethyl)aminoethyl]thiourea

https://huagongshe.com/reaction/972629

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(2-Isothiocyanatoethyl)dimethylamineHCID 3853726—
ReactantN-[2-(4-methyl-5-oxazolyl)ethyl]ethylenediamineHCID 20557941—
ProductN-(2-Dimethylaminoethyl)-N'-[2-(2-(4-methyl-5-oxazolyl)ethyl)aminoethyl]thioureaHCID 20557897—

Reaction Steps

By the procedure of Example 40(a)(ii), N-[2-(4-methyl-5-oxazolyl)ethyl]ethylenediamine [prepared by reacting ethylenediamine with 5-(2-chloroethyl)-4-methyloxazole] is reacted with 2-dimethylaminoethyl isothiocyanate to give the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04053473
Source datasetuspto-grants-1977_10
ORD IDord-f10c3bf6fda745f997d85d18e4fac6e9
Source noteuspto-grants-1977_10