HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → N-(4-fluorophenyl)adamantane-1-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 4-Fluoroaniline | HCID 9731 | — |
| Reactant | 1-Adamantanecarbonyl chloride | HCID 98915 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | N-(4-fluorophenyl)adamantane-1-carboxamide | HCID 331251 | — |
Reaction Steps
Subject 2.29 g. of adamantane carboxylic acid chloride (11.5 mmoles) 1.11 g. (10 mmoles) of p-fluoro-aniline and 4.0 ml. of triethylamine to the process of Example 11. Crystallize the residue obtained thereby from ethyl ether to yield the title product, m.p. 170°-171° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04053509 |
| Source dataset | uspto-grants-1977_10 |
| ORD ID | ord-712c371a6edf4c4cbf7e8f8dccb1a2f6 |
| Source note | uspto-grants-1977_10 |