HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → N-[4-(Trifluoromethyl)phenyl]tricyclo[3.3.1.13,7]decane-1-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 4-(Trifluoromethyl)aniline | HCID 9964 | — |
| Reactant | 1-Adamantanecarbonyl chloride | HCID 98915 | — |
| Solvent | Methylenechloride Hexane | HCID 21226440 | — |
| Product | N-[4-(Trifluoromethyl)phenyl]tricyclo[3.3.1.13,7]decane-1-carboxamide | HCID 8116872 | — |
Reaction Steps
Subject 2.0 g. of adamantane carboxylic acid chloride 1.6 g. (10 mmoles) of p-trifluoromethylaniline and 5.0 ml. of triethylamine to the process of Example 11. Crystallize the residue obtained thereby from a mixture of methylene chloride-hexane to obtain the product of this Example, m.p. 189°-193° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04053509 |
| Source dataset | uspto-grants-1977_10 |
| ORD ID | ord-d217edbaff714d86b1e174d9060803f5 |
| Source note | uspto-grants-1977_10 |