Isopropanol → Benzene, 1,3-dichloro-5-nitro-

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Reaction Steps

207 parts of 2,6-dichloro-4-nitroaniline is introduced into 300 parts of isopropanol and 9 parts of water; 200 parts of concentrated (98 wt%) sulfuric acid is then added to the mixture. At 50° C., 170 parts of isopropyl nitrite is run in, nitrogen being evolved. The mixture is cooled, 800 parts of water is added, and suction filtration carried out. There is obtained 188 parts (98% of theory) of 3,5-dichloronitrobenzene, m.p.: 59° - 62° C.

Provenance & Evidence