Isopropanol → Benzene, 1,3-dichloro-5-nitro-

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Reaction Steps

207 parts of 2,6-dichloro-4-nitroaniline is introduced into 1,800 parts of isopropanol and 18,000 parts of water; 700 parts of concentrated (98 wt%) sulfuric acid is then added. At 60° C., a solution of 140 parts of sodium nitrite in 240 parts of water is slowly run in. The mixture is cooled and suction filtered. There is obtained 190 parts (99% of theory) of 3,5-dichloronitrobenzene, m.p.: 61° - 62°.

Provenance & Evidence