Thionyl Chloride → HCID 20263942, compound

HRID 972870Notes

Reaction equation

HRID 972870 reaction equation
[CH2:1]([O:8][C:9]1[C:10]([CH3:19])=[N:11][CH:12]=[C:13]([CH:17]=[CH2:18])[C:14]=1[CH2:15]O)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.S(Cl)([Cl:22])=O>C1C=CC=CC=1>[CH3:19][C:10]1[C:9]([O:8][CH2:1][C:2]2[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=2)=[C:14]([CH2:15][Cl:22])[C:13]([CH:17]=[CH2:18])=[CH:12][N:11]=1

Participants

4

Reactant 2

HCID 24386Thionyl ChlorideHCID 20264049HCID 20264049, compound

Product 1

HCID 20263942HCID 20263942, compound

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent2×

Procedure

To a solution of 0.1 mole of 3-benzyloxy-4-hydroxymethyl-2-methyl-5-vinylpyridine in 500 ml. of benzene is added dropwise with cooling a solution of 0.11 mole of thionyl chloride in 50 ml. benzene. The reaction mixture is stirred for 1 hour and then filtered to give 2-methyl-3-benzyloxy-4-chloromethyl-5-vinylpyridine.

Workup

  1. filtrationfiltered

Sources & evidence

ORD record
ord-6bcef042be514c18a019cebf67809d40
Source dataset
uspto-grants-1977_10
Patent number
US04053606

Reaction notes

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